+ Cefepime* 2 g IV q8h If non-life threatening penicillin or cephalosporin allergy: Substitute meropenem* 2 g IV q8h for cefepime If life threatening penicillin allergy: Substitute aztreonam* 2 g IV q6h for cefepime Presence of CSF shunt Aerobic gram-negative bacilli (e.g., Pseudomonas) Coag-negative Pharmacokinetic parameters for Cefepime following a single intramuscular injection are summarized in Table 8. In the presence of renal insufficiency, hemodialysis, not peritoneal dialysis, is recommended to aid in the removal of Cefepime from the body. Cefepime Accession Number DB01413 Description. Aminosyn™ II 4.25% with electrolytes and calcium. It works by stopping the growth of bacteria. Hope your query is answered. Cefepime is a cephalosporin (SEF a low spor in) antibiotic. Cefepime and methadone do not interact with each other but you must not take grapefruit juice with methadone. These solutions may be stored up to 24 hours at controlled room temperature 20°C to 25°C (68°F to 77°F) or 7 days in a refrigerator 2°C to 8°C (36°F to 46°F). amoxicillin, doxycycline, metronidazole, azithromycin, cephalexin, ciprofloxacin, Keflex, clindamycin, Augmentin, levofloxacin. The following adverse reactions (Table 5) were identified in clinical trials conducted in North America (n=3,125 Cefepime-treated patients). Generic Name: cefepime (as hydrochloride) Product Name: Cefepime Alphapharm Indication: What cefepime is used for. In addition to the adverse reactions reported during the North American clinical trials with Cefepime, the following adverse reactions have been reported during worldwide postmarketing experience. Cefepime for Injection, USP is a sterile, dry mixture of Cefepime hydrochloride and L-arginine. No data are available in patients with septic shock. This medication belongs to a class of drugs known as cephalosporin antibiotics . Make sure your partner is also treated. There appeared to be a decrease in Cefepime total body clearance as a function of creatinine clearance. MAXIPIME (cefepime hydrochloride, USP) is a semi-synthetic, cephalosporin antibacterial for parenteral administration. As with other cephalosporins, the color of Cefepime for injection powder, as well as its solutions tend to darken depending on storage conditions; however, when stored as recommended, the product potency is not adversely affected. Encephalopathy (disturbance of consciousness including confusion, hallucinations, stupor, and coma), aphasia, myoclonus, seizures, and nonconvulsive status epilepticus have been reported. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Use of Cefepime for injection in these age groups is supported by evidence from adequate and well-controlled studies of Cefepime in adults with additional pharmacokinetic and safety data from pediatric trials [see Clinical Pharmacology (12.3)]. Parenteral drugs should be inspected visually for particulate matter before administration. For non-prescription products, read the label or package ingredients carefully. Intramuscular and Intravenous Cefepime for Injection. A similar safety profile was seen in clinical trials of pediatric patients. Cefepime for injection vials are compatible at concentrations between 1 mg per mL and 40 mg per mL with the following intravenous infusion fluids: 0.9% Sodium Chloride Injection, 5% and 10% Dextrose Injection, M/6 Sodium Lactate Injection, 5% Dextrose and 0.9% Sodium Chloride Injection, Lactated Ringers and 5% Dextrose Injection, Normosol™-R, and Normosol™-M in 5% Dextrose Injection. 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